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It's possible, but you'll have to do the NCR quests first, since helping Yes Man will activate Don't Tread On The Bear real quick, so you do all the NCR quests up the Hoover Dam battle, then you do the Yes Man's quests, you'll lose your reo with the NCR pretty quick but you'll get to do all those quests.

My Advice? Save the game as soon as you have the platinum chip, or before confronting Benny, this way you'll get to do all the High Notoriety Factions and see all alternative endings.

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