yeah you can kill mr house, or you can have the brotherhood form an alliance with mr. house
The part about them formiing an alliance with house is a lie you can't save them if your working with house
I assume you mean if you're working for him, in which case no, you have to kill them. If you work for Yes Man or the NCR you can form an alliance with them.
The above comment is incorrect, too. With Yes Man you can do their missions, become one, be their ally, etc, but the only way you can enlist their help in the Second Battle of Hoover Dam is if you are siding with the NCR specifically. Otherwise you just have to 'ignore' them with Yes Man, and kill them with Mr. House or Caesar's Legion.